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Yes, titanium dioxide is generally considered safe to use in makeup. It is a common ingredient used for its pigmenting and UV-blocking properties. The FDA has approved its use in cosmetics, including those used around the eyes.
However, there are certain concerns when titanium dioxide is inhaled in large amounts, such as in the form of loose powders, or when it is used in nanomaterial form which have a potential to penetrate the skin barrier. It's generally considered safe for topical use in traditional cosmetic products like foundations, creams or lotions.
As with any cosmetic product, if you experience any adverse reaction such as redness, irritation, or breakouts, you should discontinue use and consult your dermatologist.
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